Analytical Method Development and Validation of Dimethoate Pesticide using HPLC Method

Analytical Method Development and Validation of Estimation Method for Sotalol Hydrochloride Tablets by Using Rp-hplc

The present investigation describes about a simple, economic, selective, accurate, precise Reverse phase High performance liquid chromatographic method for the estimation of Sotalol Hydrochloride in pharmaceutical dosage forms. Sotalol Hydrochloride was well eluted using a C18 column of dimension 100 × 4.6, 5μm and Mobile phase consisting of Acetonitrile: 20 mM Ammonium acetate buffer (pH-6): M...

development and validation of a new hplc analytical method for the quality control of clindamycin capsules

Stability Indicating HPLC Method Development and Validation

High performance liquid chromatography (HPLC) is an integral analytical tool in assessing drug product stability. HPLC methods should be able to separate, detect, and quantify the various drug-related degradants that can form on storage or manufacturing, plus detect and quantify any drug-related impurities that may be introduced during synthesis. Forced degradation studies of new chemical entit...

Hplc Method Development and Validation: an Overview

High performance liquid chromatography (HPLC) is an analytical technique which is proficient to separate, detect and quantify various drugs and its related degradants. An appropriate mobile phase, column, column temperature, wavelength and gradient must be found that affords suitable compatibility and stability of drug as well as degradants and impurities. This review covers the importance of R...

Analytical method development and validation of prasugrel in bulk and its pharmaceutical formulation using the RP-HPLC method

PURPOSE This study was designed to develop and validate a simple, sensitive, precise, and specific reverse phase high-performance liquid chromatographic (HPLC) method for the determination of prasugrel in bulk and its tablet dosage forms. MATERIALS AND METHODS The HPLC separation was carried out by reverse phase chromatography on an inertsil ODS-3V column (5 μm; 250 × 4.6mm(2)) with a mobile ...